Supplementary Materials

Supplementary Materials for:

A cryo-EM–based model of phosphorylation- and FKBP12.6-mediated allosterism of the cardiac ryanodine receptor

Sonali Dhindwal, Joshua Lobo, Vanessa Cabra, Demetrio J. Santiago, Ashok R. Nayak, Kelly Dryden, Montserrat Samsó*

*Corresponding author. Email: montserrat.samso{at}vcuhealth.org

This PDF file includes:

  • Fig. S1. Atomic model of the structure of RyR2-FKBP12.6.
  • Fig. S2. Degree of phosphorylation of RyR2.
  • Legends for movies S1 to S3

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Technical Details

Format: Adobe Acrobat PDF

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Other Supplementary Material for this manuscript includes the following:

  • Movie S1 (.mov format). Overall structure of RyR2.
  • Movie S2 (.avi format). Morph between conformations C1 and C2 for RyR2.
  • Movie S3 (.avi format). Morph of RyR2 with and without FKBP12.6.

Citation: S. Dhindwal, J. Lobo, V. Cabra, D. J. Santiago, A. R. Nayak, K. Dryden, M. Samsó, A cryo-EM–based model of phosphorylation- and FKBP12.6-mediated allosterism of the cardiac ryanodine receptor. Sci. Signal. 10, eaai8842 (2017).

© 2017 American Association for the Advancement of Science