Supplementary Materials

Supplementary Materials for:

The lncRNA H19 mediates breast cancer cell plasticity during EMT and MET plasticity by differentially sponging miR-200b/c and let-7b

Wu Zhou,* Xiao-lei Ye, Jun Xu, Ming-Guo Cao, Zheng-Yu Fang, Ling-Yun Li, Guang-Hui Guan, Qiong Liu, Yue-Hui Qian, Dong Xie*

*Corresponding author. Email: zhouwu{at}lsu.edu.cn (W.Z.); dxie{at}sibs.ac.cn (D.X.)

This PDF file includes:

  • Fig. S1. Git2 transcript is a predicted target of miR-200b/c.
  • Fig. S2. Cyth3 transcript is a predicted target of let-7b.
  • Fig. S3. The functional effect of let-7 assessed with a targeted antagomir.
  • Fig. S4. The role of GIT2 and CYTH3 as analyzed by RIP and in vitro assays.
  • Fig. S5. Luciferase assay results.
  • Table S1. Metastases resulting from orthotopic injection of cells from distinct clones.
  • Table S2. Clinical characteristics of MBC patients.
  • Legend for data file S1
  • Data file S2. miRNA and H19 sequences.
  • Data file S3. miRNA target information.
  • Data file S4. ArfGEF target information.
  • Data file S5. siRNA, shRNA, and PCR primer sequences.

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Citation: W. Zhou, X.-l. Ye, J. Xu, M.-G. Cao, Z.-Y. Fang, L.-Y. Li, G.-H. Guan, Q. Liu, Y.-H. Qian, D. Xie, The lncRNA H19 mediates breast cancer cell plasticity during EMT and MET plasticity by differentially sponging miR-200b/c and let-7b. Sci. Signal. 10, eaak9557 (2017).

© 2017 American Association for the Advancement of Science