Supplementary Materials

Supplementary Materials for:

Activation of master virulence regulator PhoP in acidic pH requires the Salmonella-specific protein UgtL

Jeongjoon Choi and Eduardo A. Groisman*

*Corresponding author. Email: eduardo.groisman{at}yale.edu

This PDF file includes:

  • Fig. S1. UgtL-dependent activation of the PhoP protein in mildly acidic pH is similar in WT and hns-FLAG Salmonella.
  • Fig. S2. UgtL enhances PhoP-P abundance in an MgrB-independent manner.
  • Fig. S3. UgtL enhances PhoP-P abundance posttranscriptionally.
  • Fig. S4. The UgtL and PhoQ proteins interact.
  • Fig. S5. FLAG-tagged UgtL functions as WT UgtL in vivo.
  • Fig. S6. PhoP activates transcription of the ugtL gene in mildly acidic pH and low Mg2+ conditions.
  • Fig. S7. UgtL promotes Salmonella resistance to magainin 2 in a PhoP-dependent manner.
  • Table S1. Bacterial strains and plasmids used in this study.
  • Table S2. Primers used in this study.

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Citation: J. Choi, E. A. Groisman, Activation of master virulence regulator PhoP in acidic pH requires the Salmonella-specific protein UgtL. Sci. Signal. 10, eaan6284 (2017).

© 2017 American Association for the Advancement of Science