Supplementary Materials

Supplementary Materials for:

Mitochondrial redox signaling enables repair of injured skeletal muscle cells

Adam Horn, Jack H. Van der Meulen, Aurelia Defour, Marshall Hogarth, Sen Chandra Sreetama, Aaron Reed, Luana Scheffer, Navdeep S. Chandel, Jyoti K. Jaiswal*

*Corresponding author. Email: jkjaiswal{at}cnmc.org

This PDF file includes:

  • Fig. S1. Cultured cells have abundant mitochondria near the plasma membrane that do not move substantially during plasma membrane repair.
  • Fig. S2. CCCP treatment causes poor plasma membrane repair and aberrant [Ca2+]M handling after injury.
  • Fig. S3. Acute, Ca2+-dependent mitochondrial ROS production is required for plasma membrane repair.
  • Fig. S4. Injury-triggered change in F-actin, but not microtubules, facilitates plasma membrane repair.

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Citation: A. Horn, J. H. Van der Meulen, A. Defour, M. Hogarth, S. C. Sreetama, A. Reed, L. Scheffer, N. S. Chandel, J. K. Jaiswal, Mitochondrial redox signaling enables repair of injured skeletal muscle cells. Sci. Signal. 10, eaaj1978 (2017).

© 2017 American Association for the Advancement of Science