Supplementary Materials

Supplementary Materials for:

The RNA-editing enzyme ADAR promotes lung adenocarcinoma migration and invasion by stabilizing FAK

Elianna M. Amin, Yuan Liu, Su Deng, Kay See Tan, Neel Chudgar, Marty W. Mayo, Francisco Sanchez-Vega, Prasad S. Adusumilli, Nikolaus Schultz, David R. Jones*

*Corresponding author. Email: jonesd2{at}mskcc.org

This PDF file includes:

  • Fig. S1. The genetic alteration of ADAR in TCGA cohorts.
  • Fig. S2. The impact of ADAR KD on the downstream targets and cell viability.
  • Fig. S3. The editing status of FAK in the TCGA cohort.
  • Fig. S4. ADAR does not bind to region B in FAK.
  • Fig. S5. Comparison of DNA sequences of wild-type and edited pcDNA-FAKE+I.
  • Fig. S6. Cell viability after treatment with FAK inhibitors.
  • Table S1. PCR primers.

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Citation: E. M. Amin, Y. Liu, S. Deng, K. S. Tan, N. Chudgar, M. W. Mayo, F. Sanchez-Vega, P. S. Adusumilli, N. Schultz, D. R. Jones, The RNA-editing enzyme ADAR promotes lung adenocarcinoma migration and invasion by stabilizing FAK. Sci. Signal. 10, eaah3941 (2017).

© 2017 American Association for the Advancement of Science