Supplementary Materials

Supplementary Materials for:

Resveratrol stimulates the metabolic reprogramming of human CD4+ T cells to enhance effector function

Marco Craveiro, Gaspard Cretenet, Cédric Mongellaz, Maria I. Matias, Olivier Caron, Maria C. Pedroso de Lima, Valérie S. Zimmermann, Eric Solary, Valérie Dardalhon, Vjekoslav Dulić,* Naomi Taylor*

*Corresponding author. Email: vjekoslav.dulic{at}igmm.cnrs.fr (V.D.); taylor{at}igmm.cnrs.fr (N.T.)

This PDF file includes:

  • Fig. S1. Quantification and statistical analyses of main data panels.
  • Fig. S2. Effects of resveratrol on the formation of CD4+ T cell blasts and cell counts in response to TCR engagement.
  • Fig. S3. Effect of resveratrol treatment on the expression of DNA damage signaling pathway genes.
  • Fig. S4. Sorting of naïve and memory CD4+ T cells for the assessment of phenotype and cytokine secretion profiles.
  • Fig. S5. TCR-mediated induction of HIF1A and c-Myc in human CD4+ cells is not altered by low-dose resveratrol.
  • Table S1. Antibody list.
  • Table S2. Primer sequences.

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Citation: M. Craveiro, G. Cretenet, C. Mongellaz, M. I. Matias, O. Caron, M. C. P. de Lima, V. S. Zimmermann, E. Solary, V. Dardalhon, V. Dulić, N. Taylor, Resveratrol stimulates the metabolic reprogramming of human CD4+ T cells to enhance effector function. Sci. Signal. 10, eaal3024 (2017).

© 2017 American Association for the Advancement of Science