Supplementary Materials

Supplementary Materials for:

KIF22 coordinates CAR and EGFR dynamics to promote cancer cell proliferation

Rosemary Pike, Elena Ortiz-Zapater, Brooke Lumicisi, George Santis, Maddy Parsons*

*Corresponding author. Email: maddy.parsons{at}kcl.ac.uk

This PDF file includes:

  • Fig. S1. CAR regulates proliferation in H1975 cells.
  • Fig. S2. CAR does not regulate EGFR signaling or degradation in response to EGF.
  • Fig. S3. KIF22 binds to CAR.
  • Fig. S4. KIF22 regulates cell proliferation.
  • Fig. S5. Blocking endocytosis does not alter A549 cell EGFR signaling.

[Download PDF]

Technical Details

Format: Adobe Acrobat PDF

Size: 2.14 MB


Citation: R. Pike, E. Ortiz-Zapater, B. Lumicisi, G. Santis, M. Parsons, KIF22 coordinates CAR and EGFR dynamics to promote cancer cell proliferation. Sci. Signal. 11, eaaq1060 (2018).

© 2018 American Association for the Advancement of Science