Supplementary Materials

Supplementary Materials for:

VEGF–neuropilin-2 signaling promotes stem-like traits in breast cancer cells by TAZ-mediated repression of the Rac GAP β2-chimaerin

Ameer L. Elaimy, Santosh Guru, Cheng Chang, Jianhong Ou, John J. Amante, Lihua Julie Zhu, Hira Lal Goel, Arthur M. Mercurio*

*Corresponding author. Email: arthur.mercurio{at}

This PDF file includes:

  • Fig. S1. VEGF-NRP2 signaling contributes to YAP activation.
  • Fig. S2. VEGF-NRP2 activation of Rac1 is independent of VEGFR.
  • Fig. S3. VEGF-NRP2-Rac1 regulation of Merlin phosphorylation (pSer518) is LATS-dependent.
  • Fig. S4. Expression of wild-type and S89A TAZ constructs.
  • Fig. S5. β2-chimaerin is repressed by the EMT.

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