Supplementary Materials

Supplementary Materials for:

The ion channel TRPM7 is required for B cell lymphopoiesis

Mithunah Krishnamoorthy, Fathima Hifza Mohamed Buhari, Tiantian Zhao, Patrick M. Brauer, Kyle Burrows, Eric Yixiao Cao, Vincent Moxley-Paquette, Arthur Mortha, Juan Carlos Zúñiga-Pflücker, Bebhinn Treanor*

*Corresponding author. Email: bebhinn.treanor{at}utoronto.ca

This PDF file includes:

  • Fig. S1. TRPM7 is essential for B cell development in the gut, liver, and lung.
  • Fig. S2. Basal antibody concentrations are markedly reduced in TRPM7−/− mice.
  • Fig. S3. Architecture of lymph nodes in TRPM7−/− mice.
  • Fig. S4. The myeloid population is expanded in μMT mice.
  • Fig. S5. Confirmation of MNV infection.
  • Table S1. Conditional deletion of TRPM7 in B cells does not alter embryonic survival.
  • Table S2. The proportion of T cells is increased in the peripheral lymphoid tissues of TRPM7−/− mice.
  • Table S3. The number of T cells is decreased in the spleen of TRPM7−/− mice.

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