Supplementary Materials

Supplementary Materials for:

PARP12 suppresses Zika virus infection through PARP-dependent degradation of NS1 and NS3 viral proteins

Lili Li, Hui Zhao, Ping Liu, Chunfeng Li, Natalie Quanquin, Xue Ji, Nina Sun, Peishuang Du, Cheng-Feng Qin, Ning Lu,* Genhong Cheng*

*Corresponding author. Email: ninglu{at}ibp.ac.cn (N.L.); gcheng{at}mednet.ucla.edu (G.C.)

This PDF file includes:

  • Fig. S1. A CRISPR/Cas9 screen identifies ISGs that restrict ZIKV infection.
  • Fig. S2. The expression of PARP12 can be induced by IFN and ZIKV infection.
  • Fig. S3. Construction of PARP12 knockout and PARP12-overexpressing A549 cell lines.
  • Fig. S4. The expression and expected size of PARP12 domain deletion mutants.
  • Fig. S5. Alignment of ZnF domains from PARP12 and PARP13.
  • Table S1. sgRNA sequences used for ISG knockouts.

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