Supplementary Materials

The PDF file includes:

  • Fig. S1. Eph receptor activation reduces PM EGFR abundance.
  • Fig. S2. Akt and its effector PIKfyve regulate EGFR vesicular trafficking.
  • Fig. S3. Akt is preferentially activated at the PM after EGFR stimulation.
  • Fig. S4. A1 pretreatment inhibits EGFR-promoted Akt activation.
  • Fig. S5. Distributions of cell migration distances.
  • Table S1. Primer list for RT-qPCR.
  • Legends for movies S1 to S4

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Other Supplementary Material for this manuscript includes the following:

  • Movie S1 (.avi format). Akt inhibition induces EGFR endosomal accumulation.
  • Movie S2 (.avi format). A1 stimulation induces EGFR endosomal accumulation.
  • Movie S3 (.mp4 format). A1-EphA2 interactions at cell-cell contact induce EGFR endosomal accumulation.
  • Movie S4 (.mp4 format). EGF-promoted migration in MEFs.