Supplementary Materials

This PDF file includes:

  • Fig. S1. Development of postsurgical thermal and mechanical hypersensitivity in rats.
  • Fig. S2. The lack of effect of plantar skin incision on voltage-dependent activation, voltage-dependent inactivation, and deactivation kinetics of T-currents in rat DRG neurons.
  • Fig. S3. Resting membrane potential and input resistance in rat DRG neurons from sham and postincision groups.
  • Fig. S4. Antinociceptive effect of intrathecally applied TTA-P2 in unoperated rats.
  • Fig. S5. Preemptive intrathecal application of USP5 shRNA reduces mechanical hypersensitivity after incision in WT mice, but not in CaV3.2 KO mice.

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