Supplementary Materials

This PDF file includes:

  • Fig. S1. RIPK1 kinase activity coordinates apoptosis and necroptosis.
  • Fig. S2. Characterization of NETs by electron microscopy and imaging flow cytometry.
  • Fig. S3. NET formation and cell death of human neutrophils triggered by necroptotic stimuli.
  • Fig. S4. RIPK1 kinase activity and necroptotic signaling can activate PAD4.
  • Fig. S5. Role of ROS, IFN-γ, and TNF in neutrophil necroptosis and NET formation.
  • Fig. S6. MRSA dissemination in Mlkl−/− mice and Cre activity in S100a8-Cre transgenic mice.

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