Supplementary Materials

The PDF file includes:

  • Fig. S1. ULK1/2 activity is not required for IFN-γ–induced phosphorylation of STAT1.
  • Fig. S2. Effects of targeted disruption of Ulk1/2 gene expression on IFN-γ–dependent gene transcription.
  • Fig. S3. Genes differentially expressed in both Ulk1/2+/+ and Ulk1/2−/− MEFs after IFN-γ treatment.
  • Fig. S4. Genes differentially expressed only in Ulk1/2+/+ MEFs after IFN-γ treatment.
  • Fig. S5. Genes differentially expressed only in Ulk1/2−/− MEFs after IFN-γ treatment.
  • Fig. S6. GO analysis of IFN-γ–dependent differentially expressed genes.
  • Fig. S7. Inhibition of autophagy does not affect transcription of antiviral ISGs.
  • Fig. S8. Genomic location for the ULK1 sgRNA in the human ULK1 open reading frame.
  • Legends for Tables S1 to S8

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Other Supplementary Material for this manuscript includes the following:

  • Table S1 (Microsoft Excel format). GO analysis of putative ULK1 interactors in untreated versus IFN-γ–treated KT-1 cells identified by mass spectrometry analysis.
  • Table S2 (Microsoft Excel format). GO analysis of putative ULK1 interactors identified after IFN-γ stimulation by mass spectrometry analysis.
  • Table S3 (Microsoft Excel format). Genes differentially expressed in both Ulk1/2+/+ and Ulk1/2−/− MEFs after IFN-γ treatment.
  • Table S4 (Microsoft Excel format). Genes differentially expressed only in Ulk1/2+/+ MEFs after IFN-γ treatment.
  • Table S5 (Microsoft Excel format). Genes differentially expressed only in Ulk1/2−/− MEFs after IFN-γ treatment.
  • Table S6 (Microsoft Excel format). GO analysis of differentially expressed genes identified in both Ulk1/2+/+ and Ulk1/2−/− MEFs after IFN-γ treatment.
  • Table S7 (Microsoft Excel format). GO analysis of differentially expressed genes identified only in Ulk1/2+/+ MEFs after IFN-γ treatment.
  • Table S8 (Microsoft Excel format). GO analysis of differentially expressed genes identified only in Ulk1/2−/− MEFs after IFN-γ treatment.