Supplementary Materials

This PDF file includes:

  • Fig. S1. Targeting strategy for the GRK2-S670A KI mice, screening, and baseline characteristics.
  • Fig. S2. Adult fibroblast migration is not affected by the S670A mutation in GRK2.
  • Fig. S3. Total GRK2 levels in the AAR are not altered post-IR injury, and immunogold electron microscopy suggests a role for phosphorylation of Ser670 in GRK2 for mitochondrial translocation.
  • Fig. S4. Raw baseline OCR recordings from adult cardiomyocytes derived from WT and GRK2-S670A KI mice subjected to an in vitro ischemia protocol.

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