Supplementary Materials

This PDF file includes:

  • Fig. S1. Concentrations of PUFA metabolites in biopsies from patients with IBS.
  • Fig. S2. Concentrations of PUFA metabolites in biopsies of all patients with IBS.
  • Fig. S3. 5-oxoETE does not induce somatic or visceral inflammation in vivo.
  • Fig. S4. 5-oxoETE induces Ca2+ flux in mouse sensory neurons.
  • Fig. S5. Mrgprd immunoreactivity is observed in mouse colon.
  • Fig. S6. Mrgprd immunoreactivity is not observed in the colon of Mrgprd-deficient mice.

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