Supplementary Materials

This PDF file includes:

  • Fig. S1. Basal Ca2+ homeostasis in HEK WT and KO cell lines.
  • Fig. S2. Comparisons of photoreleased i-IP3–evoked global Ca2+ signals and local Ca2+ puffs in HEK WT cells in the absence and presence of 20 μM ryanodine.
  • Fig. S3. Comparison of Ca2+ puffs evoked by photoreleased i-IP3 in the presence and absence of extracellular Ca2+ in EGTA-loaded HEK cells solely expressing type 1, 2, or 3 IP3Rs.

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