Supplementary Materials

This PDF file includes:

  • Fig. S1. Clinical characteristics.
  • Fig. S2. Cerebellar architecture and protein abundance in age-matched RESTTG and WT mice.
  • Fig. S3. Increased REST expression contributes to infiltrative SHH-driven MB development.
  • Fig. S4. Differential regulation of PTCH1 expression by REST in MB tumors and CGNPs.
  • Fig. S5. REST and SUV39H1 do not coimmunoprecipitate in DAOY cells.
  • Fig. S6. Increased REST expression increases AKT phosphorylation at Ser473.
  • Fig. S7. REST-dependent AKT phosphorylation in cell lines.
  • Table S1. Synergy between MS275 and UNC0638.
  • Table S2. IC50 values for UW228 and DAOY cells treated with MK2206.
  • Table S3. Antibodies for IHC, qChIP (quantitative ChIP), and Western blotting assays.
  • Table S4. Primers for qChIP and qRT-PCR assays.

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