Supplementary Materials

This PDF file includes:

  • Fig. S1. Lattice contacts in the TrioC crystal structure.
  • Fig. S2. Sequence alignment of TrioC and related GEF modules.
  • Fig. S3. HDX-MS data for TrioC R2150W.
  • Fig. S4. Quantification of Trio variant expression in HEK293 cells.

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