Supplementary Materials

This PDF file includes:

  • Fig. S1. Lectin binding and gating of HC−/− B cells.
  • Fig. S2. Gating schemes and IgD surface expression of specific B cell populations.
  • Fig. S3. Characterization of CD19-, IgM-, and IgD-deficient B cells.
  • Fig. S4. B220 is not internalized upon BambL binding.
  • Fig. S5. Internalization of CD86 and intracellular increase in TNF-α in BambL-treated primary B cells.
  • Fig. S6. Stimulation of cells with BambL in the presence of cell death inhibitors.
  • Fig. S7. BambL binds to soluble Igs.
  • Fig. S8. Analysis of lymphoid lineage cells after in vivo injection of BambL.
  • Fig. S9. Analysis of myeloid lineage cells after in vivo injection of BambL.
  • Fig. S10. Non–B cells in the spleen show an increase in caspase activity upon BambL injection.
  • Fig. S11. BambL injection leads to splenomegaly and B cell accumulation in IgαTMF mice.
  • Fig. S12. Mice treated with anti–IL-7R antibody exhibit splenomegaly and B cell proliferation in the spleen.
  • Fig. S13. B. ambifaria biofilms do not secrete BambL but retain it in the cytosol.

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