Supplementary Materials

This PDF file includes:

  • Fig. S1. Mn2+ increases exosomal αSyn release.
  • Fig. S2. Exosomes were internalized through caveolin-mediated endocytosis.
  • Fig. S3. GFP_Syn cell–derived exosomes induce neuronal cell death in vitro.
  • Fig. S4. Visualization of cell-to-cell transmission of αSyn through protein fragment complementation assays.
  • Fig. S5. Vehicle-stimulated GFP_Syn cell–derived exosomes result in minimal αSyn pathology in vivo.

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