Supplementary Materials

This PDF file includes:

  • Fig. S1. HIPK2 is involved in antiviral immunity.
  • Fig. S2. HIPK2 is an ISG.
  • Fig. S3. HIPK2 facilitates the induction of type I IFN.
  • Fig. S4. HIPK2 is involved in antiviral immune signaling.
  • Fig. S5. HIPK2 translocates to nucleus and is cleaved after virus infection.
  • Fig. S6. HIPK2 phosphorylates ELF4 at Ser369 and contributes to its binding to type I IFN promoters.
  • Fig. S7. HIPK2 promotes IFN-αβ transcription, and type I IFNs augment HIPK2 expression.
  • Table S1. Guide RNA used in this study.
  • Table S2. Primers used in this study.

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