Supplementary Materials

This PDF file includes:

  • Fig. S1. Graphical summary of the image analysis pipeline.
  • Fig. S2. Additional analysis and TNF concentration for data presented in Fig. 1.
  • Fig. S3. Additional stimulus combinations for Figs. 2 and 3.
  • Fig. S4. Full gels and quantification of Western blots in Fig. 4.
  • Fig. S5. Increased abundance of MyD88 or TRAF6 after primary stimulation cannot bypass tolerance.
  • Fig. S6. IRAK1 modification and clustering with varied recovery periods.
  • Fig. S7. IRAK1 mutant screen and KO characterization.
  • Fig. S8. Additional IRAK1 WT and KD-Clover characterization.

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