Supplementary Materials

This PDF file includes:

  • Fig. S1. Analysis of intermediate cell populations during library screening.
  • Fig. S2. Normalized recruitment of tSH2-WT and mSH2 biosensors.
  • Fig. S3. Effect of changing binding affinity or biosensor concentration on the readout from the biosensor.
  • Fig. S4. Comparison of biosensor responses.
  • Table S1. Protein sequences of mSH2, SPY992, and SPY1148.
  • Table S2. Primer sequences.
  • Table S3. Peptides used for library screening.

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