Supplementary Materials

This PDF file includes:

  • Fig. S1. Protein interactions and cellular trafficking of GluN2Bwt- and GluN2B(P553T)-containing NMDARs.
  • Fig. S2. Altered biophysical properties of heterotrimeric GluN1-GluN2A-GluN2B(P553T) NMDARs.
  • Fig. S3. GluN2B(P553T) mutation alters GluA1 abundance in hippocampal neurons.
  • Fig. S4. Alignment of eumetazoan iGluRs showing the residues conservation of Pro553 and Phe653.
  • Table S1. Untargeted analysis of plasma sphingolipid profile in the GRIN2B(P553T) patient before and after L-serine dietary supplementation.
  • References (78, 79)

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