Supplementary Materials

This PDF file includes:

  • Fig. S1. TNFR1 clusters occur in multiple adherent cell types.
  • Fig. S2. TNFR1 molecules increase homotypic associations in response to ligand binding.
  • Fig. S3. TNFR1 clusters do not require membrane microdomains or cytoskeleton for assembly.
  • Fig. S4. AnSEC analysis of titration of TNFR1 with scTNF╬▒.
  • Fig. S5. Differential cytokine release in response to mutant scTNF╬▒ binding.
  • Fig. S6. TNFR1 clusters do not change association with complex I proteins or MLK3 in response to TNF.

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