Supplementary Materials

This PDF file includes:

  • Fig. S1. Schematic representation of generated GST fusion proteins encoding truncated D1RIL3 segments.
  • Fig. S2. TAT fusion peptides are able to cross both the placenta and blood-brain barrier, and TAT-D1Rpep is able to disrupt the D1R-SynGAP interaction.
  • Fig. S3. Cell migration is delayed in cultured MGE explants treated with TAT-D1Rpep in vitro.
  • Fig. S4. TAT-D1Rpep disrupts the D1R-SynGAP interaction in cultured MGE neurons.
  • Fig. S5. TAT-D1Rpep disrupts the D1R-SynGAP interaction in cultured glutamatergic neurons.
  • Fig. S6. SynGAP knockdown decreases the effects of D1R activation on cortactin proteolysis and PKA phosphorylation.

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