Supplementary Materials

This PDF file includes:

  • Fig. S1. Phenotypic characterization of conditional Epas1f/−,Cre mice.
  • Fig. S2. Structure and function of CBs from Epas1-null mice.
  • Fig. S3. Electrophysiological properties of CB glomus cells from wild-type and Epas1-null mice.
  • Fig. S4. Glomus cell responsiveness to acute hypoxia and HVR in NDUFA4L2-null mice.
  • Fig. S5. Loss of secretory activity in response to acute hypoxia in COX4I2-null mice.
  • Fig. S6. Generation of TH-NDUFA4L2 mice.
  • Fig. S7. Generation of TH-COX4I2 mice.

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