Supplementary Materials

The PDF file includes:

  • Fig. S1. In situ DYn-2 treatment alters EGFR-dependent ERK phosphorylation.
  • Fig. S2. OxRAC method validation and controls.
  • Fig. S3. Redox regulation of protein kinases and phosphatases.
  • Fig. S4. EGF-dependent redox regulation of AAA ATPases and small GTPases.
  • Fig. S5. Biochemical properties of the identified oxidized cysteine residues.
  • Legends for data files S1 to S4

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Other Supplementary Material for this manuscript includes the following:

  • Data file S1 (Microsoft Excel format). Table of all cysteine residues detected, their LC-MS information and intensities, and redox regulation.
  • Data file S2 (Microsoft Excel format). PANTHER and Reactome annotations for peptides (and associated genes) assigned to each temporal cluster.
  • Data file S3 (Microsoft Excel format). IPA canonical pathways enriched at each time point.
  • Data file S4 (Microsoft Excel format). Representation of Pfam domain and family annotations within the OxRAC dataset.