Supplementary Materials

This PDF file includes:

  • Fig. S1. PACRG coelutes with endogenous LUBAC components.
  • Fig. S2. PACRG restores defective p65 translocation in SHARPIN-deficient cells.
  • Fig. S3. PACRG stabilizes LUBAC.
  • Fig. S4. PACRG protects against STS- and MPP+-induced apoptotic cell death.
  • Fig. S5. TNF treatment of PACRG-silenced MEFs does not activate caspase-3.
  • Table S1. Antibodies used in this study.

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