Supplementary Materials

The PDF file includes:

  • Fig. S1. RT-PCR amplification products.
  • Fig. S2. The purity of resident macrophages in culture was higher than 95%.
  • Fig. S3. Cell counts and absolute cytokine concentrations in cultures of spleen, liver, and lung macrophages.
  • Fig. S4. Expression and secretion of IL-10 in resident macrophages from different organs.
  • Fig. S5. Comparison of plasma concentrations for LTB4, LTC4, and a-LTE4.
  • Fig. S6. Dose-dependent effect of MK-886 on LPS-induced plasma concentrations of TNF.
  • Fig. S7. Plasma concentrations of eicosanoids in LPS-injected rats pretreated with MK-886 or vehicle.
  • Table S1. Primers used in quantitative RT-PCR.
  • Table S2. Analytes evaluated by LC-MS/MS.
  • Legends for movies S1 and S2

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Other Supplementary Material for this manuscript includes the following:

  • Movie S1 (.mp4 format). Animated graph of cytokine EMI at 30 min after LPS.
  • Movie S2 (.mp4 format). Animated graph of cytokine EMI at 80 min after LPS.