RT Journal Article SR Electronic T1 Regulation of Enzymatic Activity and Gene Expression by Membrane Fluidity JF Science's STKE JO Sci. STKE FD American Association for the Advancement of Science SP pe1 OP pe1 DO 10.1126/stke.2000.62.pe1 VO 2000 IS 62 A1 Los, Dmitry A. A1 Murata, Norio YR 2000 UL http://stke.sciencemag.org/content/2000/62/pe1.abstract AB Changes in the cellular environment can lead to alterations in the fluidity of the membranes of prokaryotes and eukaryotes. Changes in temperature and osmotic conditions are two of the best-studied stresses that can affect membrane fluidity. Los and Murata discuss the types of sensors that detect these changes in membrane fluidity and the types of signals that are generated.