PT  - JOURNAL ARTICLE
AU  - Chellappan, Srikumar P.
TI  - HOG on the Promoter: Regulation of the Osmotic Stress Response
AID  - 10.1126/stke.2001.93.pe1
DP  - 2001 Jul 31
TA  - Science's STKE
PG  - pe1--pe1
VI  - 2001
IP  - 93
4099  - http://stke.sciencemag.org/content/2001/93/pe1.short
4100  - http://stke.sciencemag.org/content/2001/93/pe1.full
SO  - Sci. STKE2001 Jul 31; 2001
AB  - Members of the mitogen-activated protein (MAP) kinase family regulate transcription through phosphorylation of specific transcription factors. New studies indicate that this process may be more complex than previously anticipated. The yeast Hog1 protein kinase (a homolog of the mammalian p38 MAP kinase) interacts with transcription factors and perhaps with the general transcription machinery at target promoters. Chellappan discusses the recent results and their implications for understanding control of transcription by stress-activated MAP kinases.