RT Journal Article
SR Electronic
T1 Meeting Report: In Silico Cell Signaling Underground
JF Science's STKE
JO Sci. STKE
FD American Association for the Advancement of Science
SP pe8
OP pe8
DO 10.1126/stke.2003.170.pe8
VO 2003
IS 170
A1 Werner, Eric
YR 2003
UL http://stke.sciencemag.org/content/2003/170/pe8.abstract
AB A report of the meeting "International Conference on Systems Biology," Karolinska Institute, Stockholm, Sweden, 13 to 15 December 2002. Cell signaling is becoming a darling of systems biology. Because cell signaling is a relatively well understood, complex, but not overwhelming area of biology, it has become an attractive focal point for computational modeling and simulation efforts by engineers, computer scientists, mathematicians, and systems biologists. The flow of information within and between cells points to a possible conceptual and theoretical kinship with similar phenomena in computer networks, communication theory, information theory, and information flow in engineered systems. Although still in its infancy, the field is experiencing a growth in interest, as evidenced by the poster sessions at the recent International Conference on Systems Biology (ICSB 2002). This report focuses on some of those efforts to mathematically model and simulate cell signaling and signal transduction networks.