PT  - JOURNAL ARTICLE
AU  - Ewbank, Jonathan J.
AU  - Gorvel, Jean-Pierre
AU  - Vivier, Eric
TI  - Book Review: A Widely Conserved Smell of Danger
AID  - 10.1126/stke.2003.171.pe9
DP  - 2003 Feb 25
TA  - Science's STKE
PG  - pe9--pe9
VI  - 2003
IP  - 171
4099  - http://stke.sciencemag.org/content/2003/171/pe9.short
4100  - http://stke.sciencemag.org/content/2003/171/pe9.full
SO  - Sci. STKE2003 Feb 25; 2003
AB  - Review and commentary on Toll-like Receptor Family Members and Their Ligands, edited by Bruce Beutler and Hermann Wagner. Springer-Verlag, Berlin, Heidelberg, 2002, 192 pp. $95.00, ISBN: 3-540-43560-3 With more than 150 original articles and more than a dozen reviews having been published in 2002 on the Toll-like receptor (TLR) family, the book Toll-like Receptor Family Members and Their Ligands provides a timely overview of the role of TLRs in innate immunity. The book provides chapters on the receptors, their ligands, and the signaling cascades activated. Highlighted in this book review are the chapters on the evolution of the TLRs, the receptor-ligand specificity, and the possible cross-talk between TLR signaling pathways and mitogen-activated protein kinase pathways.