RT Journal Article
SR Electronic
T1 Protein Phosphatases
JF Science's STKE
JO Sci. STKE
FD American Association for the Advancement of Science
SP tr8
OP tr8
DO 10.1126/stke.2732005tr8
VO 2005
IS 273
A1 Salton, Stephen R.
YR 2005
UL http://stke.sciencemag.org/content/2005/273/tr8.abstract
AB This Teaching Resource provides lecture notes and slides for a class covering the structure and function of protein phosphatases and is part of the course "Cell Signaling Systems: A Course for Graduate Students." The lecture begins with a discussion of the importance of phosphatases in physiology, recognized by the award of a Nobel Prize in 1992, and then proceeds to describe the two types of protein phosphatases: serine/threonine and tyrosine phosphatases. The information covered includes the structure, regulation, and substrate specificity of protein phosphatases, with an emphasis on their importance in disease and clinical settings.