PT - JOURNAL ARTICLE AU - Adler, Elizabeth M. AU - Gough, Nancy R. AU - Ray, L. Bryan TI - Focus Issue: Turning the Corner in Cancer Therapy? AID - 10.1126/stke.3372006eg8 DP - 2006 May 30 TA - Science's STKE PG - eg8--eg8 VI - 2006 IP - 337 4099 - http://stke.sciencemag.org/content/2006/337/eg8.short 4100 - http://stke.sciencemag.org/content/2006/337/eg8.full SO - Sci. STKE2006 May 30; 2006 AB - This week’s issues of Science and Science’s STKE are devoted to cancer research and to exploring how recent discoveries may impact our ability to diagnose and treat cancer. Science's STKE focuses on mechanisms by which growth factor–mediated stimulation of hypoxia-inducible factor signaling contributes to cancer progression and research that suggests a role as a tumor suppressor for a splicing variant of the c-H-ras oncogene.