RT Journal Article SR Electronic T1 Focus Issue: Turning the Corner in Cancer Therapy? JF Science's STKE JO Sci. STKE FD American Association for the Advancement of Science SP eg8 OP eg8 DO 10.1126/stke.3372006eg8 VO 2006 IS 337 A1 Adler, Elizabeth M. A1 Gough, Nancy R. A1 Ray, L. Bryan YR 2006 UL http://stke.sciencemag.org/content/2006/337/eg8.abstract AB This week’s issues of Science and Science’s STKE are devoted to cancer research and to exploring how recent discoveries may impact our ability to diagnose and treat cancer. Science's STKE focuses on mechanisms by which growth factor–mediated stimulation of hypoxia-inducible factor signaling contributes to cancer progression and research that suggests a role as a tumor suppressor for a splicing variant of the c-H-ras oncogene.