PT  - JOURNAL ARTICLE
AU  - Schlegel, Robert A.
AU  - Williamson, Patrick
TI  - P.S. to PS (Phosphatidylserine)–Pertinent Proteins in Apoptotic Cell Clearance
AID  - 10.1126/stke.4082007pe57
DP  - 2007 Oct 16
TA  - Science's STKE
PG  - pe57--pe57
VI  - 2007
IP  - 408
4099  - http://stke.sciencemag.org/content/2007/408/pe57.short
4100  - http://stke.sciencemag.org/content/2007/408/pe57.full
SO  - Sci. STKE2007 Oct 16; 2007
AB  - The psr protein has been proposed as the critical receptor that detects phosphatidylserine (PS) on the surface of apoptotic cells. However, for some time there has been evidence that this protein is not at the cell surface but in the nucleus. Now, the phenotype of a knockout of the Drosophila psr protein (dPSR) has discredited the identification altogether, lending impetus both to uncovering the real function of the protein and to identifying the real PS receptor. Interpretations of studies of two other genes supposedly involved in PS transport may be built on similarly shaky foundations.