RT Journal Article
SR Electronic
T1 Putting on the RITz
JF Science's STKE
JO Sci. STKE
FD American Association for the Advancement of Science
SP pe71
OP pe71
DO 10.1126/stke.4162007pe71
VO 2007
IS 416
A1 Kaech, Stefanie
A1 Banker, Gary
A1 Stork, Phillip
YR 2007
UL http://stke.sciencemag.org/content/2007/416/pe71.abstract
AB Neurons develop two types of processes, axons and dendrites, whose growth must be independently controlled. Recent research has identified the small guanosine triphosphatase Rit as a differential regulator of neurite growth. Activation of Rit enhances axonal growth, whereas inhibition of Rit promotes dendritic growth. These results imply that the reciprocal regulation of a single molecule in the same cell can achieve simultaneous regulation of axonal and dendritic growth.