RT Journal Article SR Electronic T1 Focus Issue: The Long and Short of Redox Signaling JF Science Signaling JO Sci. Signal. FD American Association for the Advancement of Science SP eg12 OP eg12 DO 10.1126/scisignal.290eg12 VO 2 IS 90 A1 Gough, Nancy R. YR 2009 UL http://stke.sciencemag.org/content/2/90/eg12.abstract AB Reduction-oxidation reactions produce reactive species that regulate cellular behavior, predominantly by posttranslationally modifying cysteine residues on target proteins. Research Articles, as well as a Perspective and Review in this issue, provide insight into the pathological potential of reactive oxygen species (ROS), as well as the important physiological signals that the reactive molecules transmit and the biological processes that they regulate.