RT Journal Article SR Electronic T1 2008: Signaling Breakthroughs of the Year JF Science Signaling JO Sci. Signal. FD American Association for the Advancement of Science SP eg1 OP eg1 DO 10.1126/scisignal.252eg1 VO 2 IS 52 A1 Adler, Elizabeth M. YR 2009 UL http://stke.sciencemag.org/content/2/52/eg1.abstract AB This year's signaling breakthroughs extended from protein crystals to cells and subcellular structures to whole genomes. Nominations included research on synapses in brains and in B cells; the evolution and regulation of signaling networks; the identification of a new class of plant hormones; insights into the causes and treatments of disease, such as cancer and schizophrenia; and a possible way to stay in shape while avoiding exercise.