RT Journal Article SR Electronic T1 New Roles for Lysosomal Trafficking in Morphogen Gradient Sensing JF Science Signaling JO Sci. Signal. FD American Association for the Advancement of Science SP pe24 OP pe24 DO 10.1126/scisignal.2002053 VO 4 IS 171 A1 Rainero, Elena A1 Norman, Jim C. YR 2011 UL http://stke.sciencemag.org/content/4/171/pe24.abstract AB The way in which cells recognize their position in a gradient of morphogen controls differentiation during embryogenesis. New findings indicate that the rate at which internalized morphogen receptors are trafficked to lysosomes is key to the accurate and precise sensing of morphogen gradients and the appropriate initiation of differentiation programs during development.