RT Journal Article
SR Electronic
T1 New Roles for Lysosomal Trafficking in Morphogen Gradient Sensing
JF Science Signaling
JO Sci. Signal.
FD American Association for the Advancement of Science
SP pe24
OP pe24
DO 10.1126/scisignal.2002053
VO 4
IS 171
A1 Rainero, Elena
A1 Norman, Jim C.
YR 2011
UL http://stke.sciencemag.org/content/4/171/pe24.abstract
AB The way in which cells recognize their position in a gradient of morphogen controls differentiation during embryogenesis. New findings indicate that the rate at which internalized morphogen receptors are trafficked to lysosomes is key to the accurate and precise sensing of morphogen gradients and the appropriate initiation of differentiation programs during development.