RT Journal Article
SR Electronic
T1 An Introduction to MATLAB
JF Science Signaling
JO Sci. Signal.
FD American Association for the Advancement of Science
SP tr7
OP tr7
DO 10.1126/scisignal.2001984
VO 4
IS 191
A1 Sobie, Eric A.
YR 2011
UL http://stke.sciencemag.org/content/4/191/tr7.abstract
AB This two-part lecture introduces students to the scientific computing language MATLAB. Prior computer programming experience is not required. The lectures present basic concepts of computer programming logic that tend to cause difficulties for beginners in addition to concepts that relate specifically to the MATLAB language syntax. The lectures begin with a discussion of vectors, matrices, and arrays. Because many types of biological data, such as fluorescence images and DNA microarrays, are stored as two-dimensional objects, processing these data is a form of array manipulation, and MATLAB is especially adept at handling such array objects. The students are introduced to basic commands in MATLAB, as well as built-in functions that provide useful shortcuts. The second lecture focuses on the differences between MATLAB scripts and MATLAB functions and describes when one method of programming organization might be preferable to the other. The principles are illustrated through the analysis of experimental data, specifically measurements of intracellular calcium concentration in live cells obtained using confocal microscopy.