PT - JOURNAL ARTICLE AU - VanHook, Annalisa M. TI - Papers of note in <em>Science</em> AID - 10.1126/scisignal.aai7888 DP - 2016 Aug 16 TA - Science Signaling PG - ec188--ec188 VI - 9 IP - 441 4099 - http://stke.sciencemag.org/content/9/441/ec188.short 4100 - http://stke.sciencemag.org/content/9/441/ec188.full SO - Sci. Signal.2016 Aug 16; 9 AB - STRUCTURAL BIOLOGYA different gate designStructure of a potassium channel reveals the mechanism of the interplay between voltage-dependent and ligand gating.J. R. Whicher, R. MacKinnon, Structure of the voltage-gated K+ channel Eag1 reveals an alternative voltage sensing mechanism. Science 353, 664–669 (2016). [Abstract]G. E. S. Toombes, K. J. Swartz, Twists and turns in gating ion channels with voltage. Science 353, 646–647 (2016). [Abstract]SLEEP RESEARCHCircadian rhythms and sleep deprivationActivity in different brain regions varies according to circadian rhythm and homeostatic sleep pressure.V. Muto, M. Jaspar, C. Meyer, C. Kussé, S. L. Chellappa, C. Degueldre, E. Balteau, A. S. Bourdiec, A. Luxen, B. Middleton, S. N. Archer, C. Phillips, F. Collette, G. Vandewalle, D.-J. Dijk, P. Maquet, Local modulation of human brain responses by circadian rhythmicity and sleep debt. Science 353, 687–690 (2016). [Abstract]C. A. Czeisler, Measuring the passage of brain time. 353, 648–649 (2016). [Abstract]