RT Journal Article
SR Electronic
T1 Paper of note in <em>Science Translational Medicine</em>
JF Science Signaling
JO Sci. Signal.
FD American Association for the Advancement of Science
SP ec218
OP ec218
DO 10.1126/scisignal.aaj2264
VO 9
IS 446
A1 Ferrarelli, Leslie K.
YR 2016
UL http://stke.sciencemag.org/content/9/446/ec218.abstract
AB AUTOIMMUNITYIL-6 signaling implicated in diabetesT cells from diabetic individuals are hyperresponsive to IL-6 stimulation, which could contribute to disease pathogenesis and may be an avenue for therapeutic intervention.C. Hundhausen, A. Roth, E. Whalen, J. Chen, A. Schneider, S. A. Long, S. Wei, R. Rawlings, M. Kinsman, S. P. Evanko, T. N. Wight, C. J. Greenbaum, K. Cerosaletti, J. H. Buckner, Enhanced T cell responses to IL-6 in type 1 diabetes are associated with early clinical disease and increased IL-6 receptor expression. Sci. Transl. Med. 8, 356ra119 (2016). [Abstract]