RT Journal Article SR Electronic T1 Papers of note in Science 357 (6357) JF Science Signaling JO Sci. Signal. FD American Association for the Advancement of Science SP eaaq0228 DO 10.1126/scisignal.aaq0228 VO 10 IS 498 A1 VanHook, Annalisa M. YR 2017 UL http://stke.sciencemag.org/content/10/498/eaaq0228.abstract AB This week’s articles identify a mutation in the acetylcholine receptor that protects poison frogs from the neurotoxin that they produce; explain a key difference between neurons from Parkinson’s patients and those from mouse models of the disease; and review the intermolecular interactions that drive the formation of membraneless intracellular compartments.