Cont (n = 19 mice) | Het (n = 13 mice) | KO (n = 11 mice) | |
Serum [PTH] (pg/ml) | 52.7 ± 1.6 | 170 ± 27.4* | 959 ± 122* |
Fold over control | +2.3 | +17.2 | |
Serum [Ca2+] (mg/dl) | 11.6 ± 0.1 | 13.4 ± 0.2* | 16.4 ± 0.5* |
% Change over control | +16 | +40 | |
Urine [Ca2+] (mg/dl) | 2.8 ± 0.4 | 3.5 ± 0.5 * | 13.4 ± 2.9* |
% Change over control | +25 | +380 | |
Body weight (g) | 8.7 ± 0.3 | 8.4 ± 0.5 | 3.8 ± 0.4* |
% Change vs. control | −56 |
*P < 0.01.