Table 2 GSEA analysis of co-regulated transcripts after EGFR inhibition in DiFi cells and Met inhibition in GTL16 cells. The gene sets have been selected based on the list presented in Table 1 and are ranked by normalized enrichment score (NES). ES, enrichment score; NOM, nominal; FDR, false discovery rate.
RankGene setSizeESNESNOM P valueFDR q value
Up
3SERUM_FIBROBLAST_CORE_DN480.442.24<0.0010.003
5PENG_RAPAMYCIN_UP280.472.06<0.0010.012
Down
1PENG_RAPAMYCIN_DN50−0.65−3.04<0.001<0.001
4SERUM_FIBROBLAST_CORE_UP52−0.61−2.90<0.001<0.001
8SCHUMACHER_MYC_UP29−0.67−2.69<0.001<0.001