Table 1

Concentration of secreted IL-2 (ng/ml). Supernatants of naive and effector TH cells were collected and IL-2 concentrations were determined with an IL-2–specific ELISA. Values are means ± SEM of three (effector) or four donors (naïve). The P values were calculated with paired two-sided Student’s t test. N.S., not significant.

Naïve TH cellsEffector TH cells
24 hours48 hours72 hours
0 μM H2O20.011 ± 0.0066.09 ± 1.211.8 ± 0.913.5 ± 1.8
100 μM H2O20.004 ± 0.00051.33 ± 0.76.88 ± 2.210.83 ± 1.9
% Inhibition by 100 μM H2O2784220
P valueN.S.0.0130.0590.45